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Glucose-Responsive Gene Delivery at Physiological pH through Tertiary-Amine Stabilized Boronate-PVA Particles Synthesized by One-Pot Reaction

We report a physiologically stable and cytocompatible glucose-responsive nonviral gene delivery system made up of boronate functionalized polymeric material. Herein, we utilize boronate cis-diol interactions to develop a glucose-responsive submicron particle (SMP) system. The stability of the borona...

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Detalles Bibliográficos
Autores principales: Morey, Mangesh, Srivastava, Akshay, Pandit, Abhay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825127/
https://www.ncbi.nlm.nih.gov/pubmed/33418878
http://dx.doi.org/10.3390/pharmaceutics13010062