4’-O-Methylbroussochalcone B as a novel tubulin polymerization inhibitor suppressed the proliferation and migration of acute myeloid leukaemia cells

BACKGROUND: Recent years, survival rates of human with high-risk acute myeloid leukaemia (AML) have not raised substantially. This research aimed to investigate the role of 4′-O-Methylbroussochalcone B, for the treatment of human AML. METHODS: Firstly, we evaluated the effects of six chalcones on AM...

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Detalles Bibliográficos
Autores principales: Liu, Ziying, Wang, Changshui, Wang, Yali, Wang, Lei, Zhang, Yueyuan, Yan, Genquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825173/
https://www.ncbi.nlm.nih.gov/pubmed/33482772
http://dx.doi.org/10.1186/s12885-020-07759-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825173/
https://www.ncbi.nlm.nih.gov/pubmed/33482772
http://dx.doi.org/10.1186/s12885-020-07759-4

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