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Examination of Physiologically‐Based Pharmacokinetic Models of Rosuvastatin

Physiologically‐based pharmacokinetic (PBPK) modeling is increasingly used to predict drug disposition and drug–drug interactions (DDIs). However, accurately predicting the pharmacokinetics of transporter substrates and transporter‐mediated DDIs (tDDIs) is still challenging. Rosuvastatin is a common...

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Detalles Bibliográficos
Autores principales: Bowman, Christine M., Ma, Fang, Mao, Jialin, Chen, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825190/
https://www.ncbi.nlm.nih.gov/pubmed/33220025
http://dx.doi.org/10.1002/psp4.12571