Combining Model‐Based Clinical Trial Simulation, Pharmacoeconomics, and Value of Information to Optimize Trial Design

The Bayesian decision‐analytic approach to trial design uses prior distributions for treatment effects, updated with likelihoods for proposed trial data. Prior distributions for treatment effects based on previous trial results risks sample selection bias and difficulties when a proposed trial diffe...

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Detalles Bibliográficos
Autores principales: Hill‐McManus, Daniel, Hughes, Dyfrig A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825194/
https://www.ncbi.nlm.nih.gov/pubmed/33314752
http://dx.doi.org/10.1002/psp4.12579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825194/
https://www.ncbi.nlm.nih.gov/pubmed/33314752
http://dx.doi.org/10.1002/psp4.12579

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