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Impact of APOE ε4 genotype on initial cognitive symptoms differs for Alzheimer’s and Lewy body neuropathology

BACKGROUND: APOE ε4 carrier status is known to increase odds of amnestic presentations with Alzheimer’s pathology. It is unknown how APOE ε4 carrier status impacts odds of specific initial cognitive symptoms in the presence of Lewy body pathology. Here we evaluate the impact of APOE ε4 genotype on i...

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Detalles Bibliográficos
Autores principales: Pillai, Jagan A., Bena, James, Bonner-Jackson, Aaron, Leverenz, James B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825215/
https://www.ncbi.nlm.nih.gov/pubmed/33485373
http://dx.doi.org/10.1186/s13195-021-00771-1