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The negative charge of the 343 site is essential for maintaining physiological functions of CXCR4

BACKGROUND: Warts, hypogammaglobulinemia, recurrent bacterial infections and myelokathexis (WHIM) syndrome is a primary immunodeficiency disease (PID) usually caused by autosomal dominant mutations in the chemokine receptor CXCR4 gene. To date, a total of nine different mutations including eight tru...

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Detalles Bibliográficos
Autores principales: Wang, Liqing, Xiong, Qiuhong, Li, Ping, Chen, Guangxin, Tariq, Nayab, Wu, Changxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825245/
https://www.ncbi.nlm.nih.gov/pubmed/33485325
http://dx.doi.org/10.1186/s12860-021-00347-9