Tetraoctylammonium, a Long Chain Quaternary Ammonium Blocker, Promotes a Noncollapsed, Resting-Like Inactivated State in KcsA

Alkylammonium salts have been used extensively to study the structure and function of potassium channels. Here, we use the hydrophobic tetraoctylammonium (TOA(+)) to shed light on the structure of the inactivated state of KcsA, a tetrameric prokaryotic potassium channel that serves as a model to its...

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Detalles Bibliográficos
Autores principales: Giudici, Ana Marcela, Díaz-García, Clara, Renart, Maria Lourdes, Coutinho, Ana, Prieto, Manuel, González-Ros, José M., Poveda, José Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825302/
https://www.ncbi.nlm.nih.gov/pubmed/33419017
http://dx.doi.org/10.3390/ijms22020490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825302/
https://www.ncbi.nlm.nih.gov/pubmed/33419017
http://dx.doi.org/10.3390/ijms22020490

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