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Diesel Exhaust Particulates Enhances Susceptibility of LPS-Induced Acute Lung Injury through Upregulation of the IL-17 Cytokine-Derived TGF-β(1)/Collagen I Expression and Activation of NLRP3 Inflammasome Signaling in Mice

Diesel exhaust particulates (DEP) adversely affect the respiratory system and exacerbate lung diseases, resulting in high mortality rates. However, its pathogenesis is complicated, and the mechanisms involved are incompletely understood. We investigated the effects of DEP pre-exposure on lipopolysac...

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Detalles Bibliográficos
Autores principales: Kim, Dong Im, Song, Mi-Kyung, Lee, Kyuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825418/
https://www.ncbi.nlm.nih.gov/pubmed/33419073
http://dx.doi.org/10.3390/biom11010067