Characterization of LDD-2633 as a Novel RET Kinase Inhibitor with Anti-Tumor Effects in Thyroid Cancer

Rearranged during transfection (RET), a receptor tyrosine kinase, is activated by glial cell line-derived neurotrophic factor family ligands. Chromosomal rearrangement or point mutations in RET are observed in patients with papillary thyroid and medullary thyroid carcinomas. Oncogenic alteration of...

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Detalles Bibliográficos
Autores principales: Lee, Hyo Jeong, Jeong, Pyeonghwa, Moon, Yeongyu, Choi, Jungil, Heo, Jeong Doo, Kim, Yong-Chul, Han, Sun-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825493/
https://www.ncbi.nlm.nih.gov/pubmed/33419162
http://dx.doi.org/10.3390/ph14010038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825493/
https://www.ncbi.nlm.nih.gov/pubmed/33419162
http://dx.doi.org/10.3390/ph14010038

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