Keap1-Nrf2 Pathway Regulates ALDH and Contributes to Radioresistance in Breast Cancer Stem Cells

Tumor recurrence after radiotherapy due to the presence of breast cancer stem cells (BCSCs) is a clinical challenge, and the mechanism remains unclear. Low levels of ROS and enhanced antioxidant defenses are shown to contribute to increasing radioresistance. However, the role of Nrf2-Keap1-Bach1 sig...

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Detalles Bibliográficos
Autores principales: Kamble, Dinisha, Mahajan, Megharani, Dhat, Rohini, Sitasawad, Sandhya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825579/
https://www.ncbi.nlm.nih.gov/pubmed/33419140
http://dx.doi.org/10.3390/cells10010083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825579/
https://www.ncbi.nlm.nih.gov/pubmed/33419140
http://dx.doi.org/10.3390/cells10010083

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