Clinical application of liquid biopsies to detect somatic BRCA1/2 mutations and guide potential therapeutic intervention for patients with metastatic breast cancer

Plasma based genotyping via cell-free DNA may identify actionable mutations for potential therapeutic intervention in patients with advanced malignancies including breast cancer. In this article, we discuss recent studies using cell-free DNA testing to identify and classify somatic BRCA1/2 mutations...

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Detalles Bibliográficos
Autores principales: Vidula, Neelima, Ellisen, Leif W., Bardia, Aditya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2021
Materias:
Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825638/
https://www.ncbi.nlm.nih.gov/pubmed/33520111
http://dx.doi.org/10.18632/oncotarget.27863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825638/
https://www.ncbi.nlm.nih.gov/pubmed/33520111
http://dx.doi.org/10.18632/oncotarget.27863

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