Improved therapeutic efficacy of unmodified anti-tumor antibodies by immune checkpoint blockade and kinase targeted therapy in mouse models of melanoma

The use of specific anti-tumor antibodies has transformed the solid cancer therapeutics landscape with the relative successes of therapies such as anti-HER2 in breast cancer, and anti-EGFR in HNSCC and colorectal cancer. However, these therapies result in toxicity and the emergence of resistant tumo...

Descripción completa

Detalles Bibliográficos
Autores principales: Pérez-Lorenzo, Rolando, Erjavec, Stephanie O., Christiano, Angela M., Clynes, Raphael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825641/
https://www.ncbi.nlm.nih.gov/pubmed/33520112
http://dx.doi.org/10.18632/oncotarget.27868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825641/
https://www.ncbi.nlm.nih.gov/pubmed/33520112
http://dx.doi.org/10.18632/oncotarget.27868

Ejemplares similares