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Self-Assembled Thermoresponsive Nanogel from Grafted Hyaluronic Acid as a Biocompatible Delivery Platform for Curcumin with Enhanced Drug Loading and Biological Activities

A hyaluronic acid-grafted poly(N-isopropylacrylamide) (HA-pNIPAM) was synthesized as a polymeric nanogel platform for encapsulation and delivery of hydrophobic bioactive compounds using curcumin as a model drug. As demonstrated by transmission electron microscopy and dynamic light scattering techniq...

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Detalles Bibliográficos
Autores principales: Luckanagul, Jittima Amie, Ratnatilaka Na Bhuket, Pahweenvaj, Muangnoi, Chawanphat, Rojsitthisak, Pranee, Wang, Qian, Rojsitthisak, Pornchai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825653/
https://www.ncbi.nlm.nih.gov/pubmed/33430269
http://dx.doi.org/10.3390/polym13020194