Comparative evaluation of integrated purification pathways for bacterial modular polyomavirus major capsid protein VP1 to produce virus-like particles using high throughput process technologies

Modular virus-like particles and capsomeres are potential vaccine candidates that can induce strong immune responses. There are many described protocols for the purification of microbially-produced viral protein in the literature, however, they suffer from inherent limitations in efficiency, scalabi...

Descripción completa

Detalles Bibliográficos
Autores principales: Gerstweiler, Lukas, Billakanti, Jagan, Bi, Jingxiu, Middelberg, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825977/
https://www.ncbi.nlm.nih.gov/pubmed/33545579
http://dx.doi.org/10.1016/j.chroma.2021.461924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825977/
https://www.ncbi.nlm.nih.gov/pubmed/33545579
http://dx.doi.org/10.1016/j.chroma.2021.461924

Ejemplares similares