Chloroquine may induce endothelial injury through lysosomal dysfunction and oxidative stress

COVID-19 is a pandemic with no end in sight. There is only one approved antiviral agent but global stocks are deemed insufficient. Despite in vitro antiviral activity, clinical trials of chloroquine and hydroxychloroquine were disappointing, and they may even impair outcomes. Chloroquine causes zebr...

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Detalles Bibliográficos
Autores principales: Gregório, PauloC., da Cunha, Regiane S., Biagini, Gilson, Bosquetti, Bruna, Budag, Júlia, Ortiz, Alberto, Sánchez-Niño, Maria Dolores, Barreto, Fellype C., Stinghen, Andréa E.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826090/
https://www.ncbi.nlm.nih.gov/pubmed/33484708
http://dx.doi.org/10.1016/j.taap.2021.115412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826090/
https://www.ncbi.nlm.nih.gov/pubmed/33484708
http://dx.doi.org/10.1016/j.taap.2021.115412

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