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Enhanced production of camptothecin by immobilized callus of Ophiorrhiza mungos and a bioinformatic insight into its potential antiviral effect against SARS-CoV-2

Camptothetin (CPT) is a quinoline alkaloid originally isolated from the Chinese tree, Camptotheca acuminata Decne. CPT was found to have anticancerous and antiviral properties. Derivatives of natural CPT, including topothecan and irinotecan are used clinically to treat a variety of cancers. Apart fr...

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Detalles Bibliográficos
Autores principales: Mamkulathil Devasia, Rajesh, Altaf, Mohammad, Fahad Alrefaei, Abdulwahed, Manoharadas, Salim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. on behalf of King Saud University. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826111/
https://www.ncbi.nlm.nih.gov/pubmed/33531790
http://dx.doi.org/10.1016/j.jksus.2021.101344