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STAT6 rs324015 Gene Polymorphism Increases Ulcerative Colitis Risk: A Case–Control Study

INTRODUCTION: Phosphorylation of signal transducer and activator of transcription 6 (STAT6) in the colonic epithelium is elevated in ulcerative colitis (UC) patients, and its inhibition prevents IL-13-associated apoptosis and barrier disruption. Recently, the STAT6 rs324015 polymorphism was reported...

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Detalles Bibliográficos
Autores principales: Dai, Lingying, Zhang, Dan, Qian, Yunzhi, Wan, Yemin, Chang, Shuchen, Qian, Haihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826160/
https://www.ncbi.nlm.nih.gov/pubmed/33500651
http://dx.doi.org/10.2147/PGPM.S271327