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Recapitulating Evolutionary Divergence in a Single Cis-Regulatory Element Is Sufficient to Cause Expression Changes of the Lens Gene Tdrd7

Mutations in cis-regulatory elements play important roles for phenotypic changes during evolution. Eye degeneration in the blind mole rat (BMR; Nannospalax galili) and other subterranean mammals is significantly associated with widespread divergence of eye regulatory elements, but the effect of thes...

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Detalles Bibliográficos
Autores principales: Roscito, Juliana G, Subramanian, Kaushikaram, Naumann, Ronald, Sarov, Mihail, Shevchenko, Anna, Bogdanova, Aliona, Kurth, Thomas, Foerster, Leo, Kreysing, Moritz, Hiller, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826196/
https://www.ncbi.nlm.nih.gov/pubmed/32853335
http://dx.doi.org/10.1093/molbev/msaa212