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Recapitulating Evolutionary Divergence in a Single Cis-Regulatory Element Is Sufficient to Cause Expression Changes of the Lens Gene Tdrd7
Mutations in cis-regulatory elements play important roles for phenotypic changes during evolution. Eye degeneration in the blind mole rat (BMR; Nannospalax galili) and other subterranean mammals is significantly associated with widespread divergence of eye regulatory elements, but the effect of thes...
Autores principales: | Roscito, Juliana G, Subramanian, Kaushikaram, Naumann, Ronald, Sarov, Mihail, Shevchenko, Anna, Bogdanova, Aliona, Kurth, Thomas, Foerster, Leo, Kreysing, Moritz, Hiller, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826196/ https://www.ncbi.nlm.nih.gov/pubmed/32853335 http://dx.doi.org/10.1093/molbev/msaa212 |
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