Quantitation of Apremilast in Beagle Dogs Plasma by UPLC-MS-MS and Its Application to Pharmacokinetic Studies

A sensitive and selective ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS-MS) method for the determination of apremilast in beagle dog plasma has been developed and successfully validated in the current study. Clopidogrel was employed as an internal standard (IS), and liqui...

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Detalles Bibliográficos
Autores principales: Xiong, Wei, Wang, Ling, Zhang, Haiyan, Tao, Xiaoqiu, Jiang, Xuehua, Liu, Zejuan, Zhao, Jiajia, Xu, Wenwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826237/
https://www.ncbi.nlm.nih.gov/pubmed/33510930
http://dx.doi.org/10.1155/2021/8881076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826237/
https://www.ncbi.nlm.nih.gov/pubmed/33510930
http://dx.doi.org/10.1155/2021/8881076

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