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SUMOylation mediates CtIP’s functions in DNA end resection and replication fork protection
Double-strand breaks and stalled replication forks are a significant threat to genomic stability that can lead to chromosomal rearrangements or cell death. The protein CtIP promotes DNA end resection, an early step in homologous recombination repair, and has been found to protect perturbed forks fro...
Autores principales: | Locke, Andrew J, Hossain, Lazina, McCrostie, Glynnis, Ronato, Daryl A, Fitieh, Amira, Rafique, Tanzeem Ahmed, Mashayekhi, Fatemeh, Motamedi, Mobina, Masson, Jean-Yves, Ismail, Ismail Hassan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826263/ https://www.ncbi.nlm.nih.gov/pubmed/33406258 http://dx.doi.org/10.1093/nar/gkaa1232 |
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