SUMOylation mediates CtIP’s functions in DNA end resection and replication fork protection

Double-strand breaks and stalled replication forks are a significant threat to genomic stability that can lead to chromosomal rearrangements or cell death. The protein CtIP promotes DNA end resection, an early step in homologous recombination repair, and has been found to protect perturbed forks fro...

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Detalles Bibliográficos
Autores principales: Locke, Andrew J, Hossain, Lazina, McCrostie, Glynnis, Ronato, Daryl A, Fitieh, Amira, Rafique, Tanzeem Ahmed, Mashayekhi, Fatemeh, Motamedi, Mobina, Masson, Jean-Yves, Ismail, Ismail Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826263/
https://www.ncbi.nlm.nih.gov/pubmed/33406258
http://dx.doi.org/10.1093/nar/gkaa1232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826263/
https://www.ncbi.nlm.nih.gov/pubmed/33406258
http://dx.doi.org/10.1093/nar/gkaa1232

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