SIAH2 regulates DNA end resection and replication fork recovery by promoting CtIP ubiquitination

Human CtIP maintains genomic integrity primarily by promoting 5′ DNA end resection, an initial step of the homologous recombination (HR). A few mechanisms have been suggested as to how CtIP recruitment to damage sites is controlled, but it is likely that we do not yet have full understanding of the...

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Detalles Bibliográficos
Autores principales: Jeong, Seo-Yeon, Hariharasudhan, Gurusamy, Kim, Min-Ji, Lim, Ji-Yeon, Jung, Sung Mi, Choi, Eun-Ji, Chang, In-Youb, Kee, Younghoon, You, Ho Jin, Lee, Jung-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561274/
https://www.ncbi.nlm.nih.gov/pubmed/36155803
http://dx.doi.org/10.1093/nar/gkac808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561274/
https://www.ncbi.nlm.nih.gov/pubmed/36155803
http://dx.doi.org/10.1093/nar/gkac808

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