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Structural dynamics of double-stranded DNA with epigenome modification

Modification of cytosine plays an important role in epigenetic regulation of gene expression and genome stability. Cytosine is converted to 5-methylcytosine (5mC) by DNA methyltransferase; in turn, 5mC may be oxidized to 5-hydroxymethylcytosine (5hmC) by ten-eleven translocation enzyme. The structur...

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Detalles Bibliográficos
Autores principales: Furukawa, Ayako, Walinda, Erik, Arita, Kyohei, Sugase, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826269/
https://www.ncbi.nlm.nih.gov/pubmed/33337470
http://dx.doi.org/10.1093/nar/gkaa1210