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Programmable gene regulation for metabolic engineering using decoy transcription factor binding sites

Transcription factor decoy binding sites are short DNA sequences that can titrate a transcription factor away from its natural binding site, therefore regulating gene expression. In this study, we harness synthetic transcription factor decoy systems to regulate gene expression for metabolic pathways...

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Detalles Bibliográficos
Autores principales: Wang, Tiebin, Tague, Nathan, Whelan, Stephen A, Dunlop, Mary J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826281/
https://www.ncbi.nlm.nih.gov/pubmed/33367820
http://dx.doi.org/10.1093/nar/gkaa1234