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Effects of codon usage on gene expression are promoter context dependent

Codon usage bias is a universal feature of all genomes. Although codon usage has been shown to regulate mRNA and protein levels by influencing mRNA decay and transcription in eukaryotes, little or no genome-wide correlations between codon usage and mRNA levels are detected in mammalian cells, raisin...

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Detalles Bibliográficos
Autores principales: Yang, Qian, Lyu, Xueliang, Zhao, Fangzhou, Liu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826287/
https://www.ncbi.nlm.nih.gov/pubmed/33410890
http://dx.doi.org/10.1093/nar/gkaa1253