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LGI1–ADAM22–MAGUK configures transsynaptic nanoalignment for synaptic transmission and epilepsy prevention

Physiological functioning and homeostasis of the brain rely on finely tuned synaptic transmission, which involves nanoscale alignment between presynaptic neurotransmitter-release machinery and postsynaptic receptors. However, the molecular identity and physiological significance of transsynaptic nan...

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Detalles Bibliográficos
Autores principales: Fukata, Yuko, Chen, Xiumin, Chiken, Satomi, Hirano, Yoko, Yamagata, Atsushi, Inahashi, Hiroki, Sanbo, Makoto, Sano, Hiromi, Goto, Teppei, Hirabayashi, Masumi, Kornau, Hans-Christian, Prüss, Harald, Nambu, Atsushi, Fukai, Shuya, Nicoll, Roger A., Fukata, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826393/
https://www.ncbi.nlm.nih.gov/pubmed/33397806
http://dx.doi.org/10.1073/pnas.2022580118