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Ultra‐mutated colorectal cancer patients with POLE driver mutations exhibit distinct clinical patterns

POLE mutations, which lead to an ultramutated phenotype in colorectal cancer (CRC), have been reported as a promising marker in immunotherapy. We performed sequencing of CRC cases in Zhejiang University (ZJU) and extracted obtainable data from recently published results, including The Cancer Genome...

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Detalles Bibliográficos
Autores principales: Hu, Hanguang, Cai, Wen, Wu, Dehao, Hu, Wangxiong, Dong Wang, Li, Mao, Jianshan, Zheng, Shu, Ge, Weiting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826451/
https://www.ncbi.nlm.nih.gov/pubmed/33125191
http://dx.doi.org/10.1002/cam4.3579