Clathrin‐mediated EGFR endocytosis as a potential therapeutic strategy for overcoming primary resistance of EGFR TKI in wild‐type EGFR non‐small cell lung cancer

OBJECTIVES: Oncogenic alterations of epidermal growth factor receptor (EGFR) signaling are frequently noted in non‐small cell lung cancer (NSCLC). In recent decades, EGFR tyrosine kinase inhibitors (TKIs) have been developed, although the therapeutic efficacy of these inhibitor is restricted to EGFR...

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Detalles Bibliográficos
Autores principales: Kim, Boyeon, Park, Young Soo, Sung, Jae Sook, Lee, Jong Won, Lee, Saet Byeol, Kim, Yeul Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826488/
https://www.ncbi.nlm.nih.gov/pubmed/33314735
http://dx.doi.org/10.1002/cam4.3635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826488/
https://www.ncbi.nlm.nih.gov/pubmed/33314735
http://dx.doi.org/10.1002/cam4.3635

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