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Role of NLRP3 Inflammasome Activation in Obesity-Mediated Metabolic Disorders

NLRP3 inflammasome is one of the multimeric protein complexes of the nucleotide-binding domain, leucine-rich repeat (NLR)-containing pyrin and HIN domain family (PYHIN). When activated, NLRP3 inflammasome triggers the release of pro-inflammatory interleukins (IL)-1β and IL-18, an essential step in i...

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Detalles Bibliográficos
Autores principales: Wani, Kaiser, AlHarthi, Hind, Alghamdi, Amani, Sabico, Shaun, Al-Daghri, Nasser M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826517/
https://www.ncbi.nlm.nih.gov/pubmed/33435142
http://dx.doi.org/10.3390/ijerph18020511