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The Mutational Concordance of Fixed Formalin Paraffin Embedded and Fresh Frozen Gastro-Oesophageal Tumours Using Whole Exome Sequencing

1. Background: The application of massively parallel sequencing has led to the identification of aberrant druggable pathways and somatic mutations within therapeutically relevant genes in gastro-oesophageal cancer. Given the widespread use of formalin-fixed paraffin-embedded (FFPE) samples in the st...

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Detalles Bibliográficos
Autores principales: Chong, Irene Y., Starling, Naureen, Rust, Alistair, Alexander, John, Aronson, Lauren, Llorca-Cardenosa, Marta, Chauhan, Ritika, Chaudry, Asif, Kumar, Sacheen, Fenwick, Kerry, Assiotis, Ioannis, Matthews, Nik, Begum, Ruwaida, Wotherspoon, Andrew, Terlizzo, Monica, Watkins, David, Chau, Ian, Lord, Christopher J., Haider, Syed, Rao, Sheela, Cunningham, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826535/
https://www.ncbi.nlm.nih.gov/pubmed/33435284
http://dx.doi.org/10.3390/jcm10020215