Inhibition of MLKL Attenuates Necroptotic Cell Death in a Murine Cell Model of Hepatic Ischaemia Injury

Background: Steatosis in donor livers poses a major risk of organ dysfunction due to their susceptibility to ischaemia-reperfusion (I/R) injury during transplant. Necroptosis, a novel form of programmed cell death, is orchestrated by receptor-interacting protein kinase 1 (RIPK1), receptor-interactin...

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Detalles Bibliográficos
Autores principales: Baidya, Raji, Gautheron, Jérémie, Crawford, Darrell H. G., Wang, Haolu, Bridle, Kim R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826539/
https://www.ncbi.nlm.nih.gov/pubmed/33435617
http://dx.doi.org/10.3390/jcm10020212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826539/
https://www.ncbi.nlm.nih.gov/pubmed/33435617
http://dx.doi.org/10.3390/jcm10020212

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