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How Insertion of a Single Tryptophan in the N-Terminus of a Cecropin A-Melittin Hybrid Peptide Changes Its Antimicrobial and Biophysical Profile

In the era of antibiotic resistance, there is an urgent need for efficient antibiotic therapies to fight bacterial infections. Cationic antimicrobial peptides (CAMP) are promising lead compounds given their membrane-targeted mechanism of action, and high affinity towards the anionic composition of b...

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Detalles Bibliográficos
Autores principales: Ferreira, Ana Rita, Teixeira, Cátia, Sousa, Carla F., Bessa, Lucinda J., Gomes, Paula, Gameiro, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826622/
https://www.ncbi.nlm.nih.gov/pubmed/33445476
http://dx.doi.org/10.3390/membranes11010048