Topical TRPM8 Agonist for Relieving Neuropathic Ocular Pain in Patients with Dry Eye: A Pilot Study

Background: Activation of TRPM8, a cold-sensing receptor located on the cornea and eyelid, has the potential to relieve the neuropathic ocular pain (NOP) in dry eye (DE) by inhibiting other aberrant nociceptive inputs. We aimed to investigate the effect of a topical TRPM8 agonist, cryosim-3 (C3), on...

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Detalles Bibliográficos
Autores principales: Yoon, Hyeon Jeong, Kim, Jonghwa, Yang, Jee Myung, Wei, Edward T., Kim, Seong Jin, Yoon, Kyung Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826705/
https://www.ncbi.nlm.nih.gov/pubmed/33445485
http://dx.doi.org/10.3390/jcm10020250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826705/
https://www.ncbi.nlm.nih.gov/pubmed/33445485
http://dx.doi.org/10.3390/jcm10020250

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