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Topical TRPM8 Agonist for Relieving Neuropathic Ocular Pain in Patients with Dry Eye: A Pilot Study
Background: Activation of TRPM8, a cold-sensing receptor located on the cornea and eyelid, has the potential to relieve the neuropathic ocular pain (NOP) in dry eye (DE) by inhibiting other aberrant nociceptive inputs. We aimed to investigate the effect of a topical TRPM8 agonist, cryosim-3 (C3), on...
Autores principales: | Yoon, Hyeon Jeong, Kim, Jonghwa, Yang, Jee Myung, Wei, Edward T., Kim, Seong Jin, Yoon, Kyung Chul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826705/ https://www.ncbi.nlm.nih.gov/pubmed/33445485 http://dx.doi.org/10.3390/jcm10020250 |
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