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Marine Collagen Hydrolysates Downregulate the Synthesis of Pro-Catabolic and Pro-Inflammatory Markers of Osteoarthritis and Favor Collagen Production and Metabolic Activity in Equine Articular Chondrocyte Organoids

Articular cartilage experiences mechanical constraints leading to chondral defects that inevitably evolve into osteoarthritis (OA), because cartilage has poor intrinsic repair capacity. Although OA is an incurable degenerative disease, several dietary supplements may help improve OA outcomes. In thi...

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Detalles Bibliográficos
Autores principales: Bourdon, Bastien, Contentin, Romain, Cassé, Frédéric, Maspimby, Chloé, Oddoux, Sarah, Noël, Antoine, Legendre, Florence, Gruchy, Nicolas, Galéra, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826754/
https://www.ncbi.nlm.nih.gov/pubmed/33430111
http://dx.doi.org/10.3390/ijms22020580