Synthesis and Biochemical Evaluation of Warhead-Decorated Psoralens as (Immuno)Proteasome Inhibitors

The immunoproteasome is a multicatalytic protease that is predominantly expressed in cells of hematopoietic origin. Its elevated expression has been associated with autoimmune diseases, various types of cancer, and inflammatory diseases. Selective inhibition of its catalytic activities is therefore...

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Detalles Bibliográficos
Autores principales: Schiffrer, Eva Shannon, Proj, Matic, Gobec, Martina, Rejc, Luka, Šterman, Andrej, Mravljak, Janez, Gobec, Stanislav, Sosič, Izidor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826781/
https://www.ncbi.nlm.nih.gov/pubmed/33445542
http://dx.doi.org/10.3390/molecules26020356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826781/
https://www.ncbi.nlm.nih.gov/pubmed/33445542
http://dx.doi.org/10.3390/molecules26020356

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