FAM188B Downregulation Sensitizes Lung Cancer Cells to Anoikis via EGFR Downregulation and Inhibits Tumor Metastasis In Vivo

SIMPLE SUMMARY: Cancer cells should acquire anoikis resistance for successful metastasis. Family with sequence similarity 188 member B (FAM188B) has been identified as a new deubiquitinase (DUB) member. Here, we demonstrate that FAM188B knockdown makes lung cancer cells sensitive to anoikis and inhi...

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Detalles Bibliográficos
Autores principales: Jang, Eun-Ju, Sung, Jee Young, Yoo, Ha-Eun, Jang, Hyonchol, Shim, Jaegal, Oh, Eok-Soo, Goh, Sung-Ho, Kim, Yong-Nyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826942/
https://www.ncbi.nlm.nih.gov/pubmed/33440835
http://dx.doi.org/10.3390/cancers13020247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826942/
https://www.ncbi.nlm.nih.gov/pubmed/33440835
http://dx.doi.org/10.3390/cancers13020247

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