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Paternal Methyl Donor Supplementation in Rats Improves Fertility, Physiological Outcomes, Gut Microbial Signatures and Epigenetic Markers Altered by High Fat/High Sucrose Diet

Increased consumption of high fat/sucrose (HF/S) diets has contributed to rising rates of obesity and its co-morbidities globally, while also negatively impacting male reproductive health. Our objective was to examine whether adding a methyl donor cocktail to paternal HF/S diet (HF/S+M) improves hea...

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Detalles Bibliográficos
Autores principales: Chleilat, Faye, Schick, Alana, Deleemans, Julie M., Reimer, Raylene A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826956/
https://www.ncbi.nlm.nih.gov/pubmed/33445606
http://dx.doi.org/10.3390/ijms22020689