One Pathway, Two Cyclic Non-Ribosomal Pentapeptides: Heterologous Expression of BE-18257 Antibiotics and Pentaminomycins from Streptomyces cacaoi CA-170360

The strain Streptomyces cacaoi CA-170360 produces the cyclic pentapeptides pentaminomycins A–H and BE-18257 A–C, two families of cyclopeptides synthesized by two non-ribosomal peptide synthetases encoded in tandem within the same biosynthetic gene cluster. In this work, we have cloned and confirmed...

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Detalles Bibliográficos
Autores principales: Román-Hurtado, Fernando, Sánchez-Hidalgo, Marina, Martín, Jesús, Ortiz-López, Francisco Javier, Carretero-Molina, Daniel, Reyes, Fernando, Genilloud, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827011/
https://www.ncbi.nlm.nih.gov/pubmed/33430167
http://dx.doi.org/10.3390/microorganisms9010135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827011/
https://www.ncbi.nlm.nih.gov/pubmed/33430167
http://dx.doi.org/10.3390/microorganisms9010135

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