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One Pathway, Two Cyclic Non-Ribosomal Pentapeptides: Heterologous Expression of BE-18257 Antibiotics and Pentaminomycins from Streptomyces cacaoi CA-170360
The strain Streptomyces cacaoi CA-170360 produces the cyclic pentapeptides pentaminomycins A–H and BE-18257 A–C, two families of cyclopeptides synthesized by two non-ribosomal peptide synthetases encoded in tandem within the same biosynthetic gene cluster. In this work, we have cloned and confirmed...
Autores principales: | Román-Hurtado, Fernando, Sánchez-Hidalgo, Marina, Martín, Jesús, Ortiz-López, Francisco Javier, Carretero-Molina, Daniel, Reyes, Fernando, Genilloud, Olga |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827011/ https://www.ncbi.nlm.nih.gov/pubmed/33430167 http://dx.doi.org/10.3390/microorganisms9010135 |
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