Synthetic Transition from Thiourea-Based Compounds to Tetrazole Derivatives: Structure and Biological Evaluation of Synthesized New N-(Furan-2-ylmethyl)-1H-tetrazol-5-amine Derivatives

Twelve novel derivatives of N-(furan-2-ylmethyl)-1H-tetrazol-5-amine were synthesized. For obtained compound 8, its corresponding substrate single crystals were isolated and X-ray diffraction experiments were completed. In the initial stage of research, in silico structure-based pharmacological pred...

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Detalles Bibliográficos
Autores principales: Szulczyk, Daniel, Bielenica, Anna, Roszkowski, Piotr, Dobrowolski, Michał A., Olejarz, Wioletta, Kmiecik, Sebastian, Podsiad, Małgorzata, Struga, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827014/
https://www.ncbi.nlm.nih.gov/pubmed/33435194
http://dx.doi.org/10.3390/molecules26020323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827014/
https://www.ncbi.nlm.nih.gov/pubmed/33435194
http://dx.doi.org/10.3390/molecules26020323

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