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Synthetic Transition from Thiourea-Based Compounds to Tetrazole Derivatives: Structure and Biological Evaluation of Synthesized New N-(Furan-2-ylmethyl)-1H-tetrazol-5-amine Derivatives
Twelve novel derivatives of N-(furan-2-ylmethyl)-1H-tetrazol-5-amine were synthesized. For obtained compound 8, its corresponding substrate single crystals were isolated and X-ray diffraction experiments were completed. In the initial stage of research, in silico structure-based pharmacological pred...
Autores principales: | Szulczyk, Daniel, Bielenica, Anna, Roszkowski, Piotr, Dobrowolski, Michał A., Olejarz, Wioletta, Kmiecik, Sebastian, Podsiad, Małgorzata, Struga, Marta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827014/ https://www.ncbi.nlm.nih.gov/pubmed/33435194 http://dx.doi.org/10.3390/molecules26020323 |
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