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Obacunone Attenuates Liver Fibrosis with Enhancing Anti-Oxidant Effects of GPx-4 and Inhibition of EMT

Obacunone, a limonin triterpenoid extracted from Phellodendronchinense Schneid or Dictamnus dasycarpusb Turcz plant, elicits a variety of pharmacological effects such as anti-inflammatory, anti-neoplastic, anti-oxidation, and anti-lung-fibrosis ones. However, the anti-fibrotic effect of obacunone an...

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Detalles Bibliográficos
Autores principales: Bai, Yongquan, Wang, Wenwen, Wang, Li, Ma, Lirong, Zhai, Dongsheng, Wang, Furong, Shi, Rui, Liu, Chaoyang, Xu, Qing, Chen, Guo, Lu, Zifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827035/
https://www.ncbi.nlm.nih.gov/pubmed/33435504
http://dx.doi.org/10.3390/molecules26020318