Cargando…
Obacunone Attenuates Liver Fibrosis with Enhancing Anti-Oxidant Effects of GPx-4 and Inhibition of EMT
Obacunone, a limonin triterpenoid extracted from Phellodendronchinense Schneid or Dictamnus dasycarpusb Turcz plant, elicits a variety of pharmacological effects such as anti-inflammatory, anti-neoplastic, anti-oxidation, and anti-lung-fibrosis ones. However, the anti-fibrotic effect of obacunone an...
Autores principales: | Bai, Yongquan, Wang, Wenwen, Wang, Li, Ma, Lirong, Zhai, Dongsheng, Wang, Furong, Shi, Rui, Liu, Chaoyang, Xu, Qing, Chen, Guo, Lu, Zifan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827035/ https://www.ncbi.nlm.nih.gov/pubmed/33435504 http://dx.doi.org/10.3390/molecules26020318 |
Ejemplares similares
-
Furan-site transformations of obacunone as potent insecticidal agents
por: Xiang, Ping, et al.
Publicado: (2018) -
Obacunone activates the Nrf2-dependent antioxidant responses
por: Xu, Shengmei, et al.
Publicado: (2016) -
Obacunone targets macrophage migration inhibitory factor (MIF) to impede osteoclastogenesis and alleviate ovariectomy-induced bone loss
por: He, Jianbo, et al.
Publicado: (2023) -
Loss of QKI in macrophage aggravates inflammatory bowel disease through amplified ROS signaling and microbiota disproportion
por: Wang, Wenwen, et al.
Publicado: (2021) -
Obacunone reduces inflammatory signalling and tumour occurrence in mice with chronic inflammation-induced colorectal cancer
por: Luo, Xiaoping, et al.
Publicado: (2020)