Functional T Cell Reactivity to Melanocyte Antigens Is Lost during the Progression of Malignant Melanoma, but Is Restored by Immunization

SIMPLE SUMMARY: Healthy humans develop spontaneous CD8+ T cell responses to melanoma associated antigens (MA) expressed by normal melanocytes. This natural autoimmunity directed against melanocytes might confer protection against the development of malignant melanoma (MM), where MA are overexpressed...

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Detalles Bibliográficos
Autores principales: Przybyla, Anna, Lehmann, Alexander A., Zhang, Ting, Mackiewicz, Jacek, Galus, Łukasz, Kirchenbaum, Greg A., Mackiewicz, Andrzej, Lehmann, Paul V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827050/
https://www.ncbi.nlm.nih.gov/pubmed/33435427
http://dx.doi.org/10.3390/cancers13020223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827050/
https://www.ncbi.nlm.nih.gov/pubmed/33435427
http://dx.doi.org/10.3390/cancers13020223

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