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A Novel Cyclic Pentadepsipeptide, N-Methylsansalvamide, Suppresses Angiogenic Responses and Exhibits Antitumor Efficacy against Bladder Cancer

SIMPLE SUMMARY: We found a novel cyclic pentadepsipeptide, N-methylsansalvamide (MSSV), and evaluated its anti-tumor action against bladder cancer using in vitro and in vivo model systems. Additionally, we report its anti-angiogenic responses both in vitro and in vivo. Moreover, acute toxicity test...

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Detalles Bibliográficos
Autores principales: Song, Jun-Hui, Park, Juhee, Park, Sung Lyea, Hwang, Byungdoo, Kim, Wun-Jae, Lee, Chan, Moon, Sung-Kwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827157/
https://www.ncbi.nlm.nih.gov/pubmed/33430488
http://dx.doi.org/10.3390/cancers13020191