Tumor-Associated Antigen xCT and Mutant-p53 as Molecular Targets for New Combinatorial Antitumor Strategies

The cystine/glutamate antiporter xCT is a tumor-associated antigen that has been newly identified in many cancer types. By participating in glutathione biosynthesis, xCT protects cancer cells from oxidative stress conditions and ferroptosis, and contributes to metabolic reprogramming, thus promoting...

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Detalles Bibliográficos
Autores principales: Magri, Jolanda, Gasparetto, Alessandro, Conti, Laura, Calautti, Enzo, Cossu, Chiara, Ruiu, Roberto, Barutello, Giuseppina, Cavallo, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827209/
https://www.ncbi.nlm.nih.gov/pubmed/33430127
http://dx.doi.org/10.3390/cells10010108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827209/
https://www.ncbi.nlm.nih.gov/pubmed/33430127
http://dx.doi.org/10.3390/cells10010108

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