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Probing the Binding Requirements of Modified Nucleosides with the DNA Nuclease SNM1A
SNM1A is a nuclease that is implicated in DNA interstrand crosslink repair and, as such, its inhibition is of interest for overcoming resistance to chemotherapeutic crosslinking agents. However, the number and identity of the metal ion(s) in the active site of SNM1A are still unconfirmed, and only a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827217/ https://www.ncbi.nlm.nih.gov/pubmed/33435514 http://dx.doi.org/10.3390/molecules26020320 |