Proniosomal Gel for Topical Delivery of Rutin: Preparation, Physicochemical Characterization and In Vitro Toxicological Profile Using 3D Reconstructed Human Epidermis Tissue and 2D Cells

Rutin (Rut) is a natural flavonol, well-known for its broad-spectrum of therapeutic effects, including antioxidant and antitumoral activities; still, it has a reduced clinical outcome due to its limited solubility in aqueous solutions. To overcome this drawback, this study proposes a novel formulati...

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Detalles Bibliográficos
Autores principales: Pinzaru, Iulia, Tanase, Alina, Enatescu, Virgil, Coricovac, Dorina, Bociort, Flavia, Marcovici, Iasmina, Watz, Claudia, Vlaia, Lavinia, Soica, Codruta, Dehelean, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827235/
https://www.ncbi.nlm.nih.gov/pubmed/33435216
http://dx.doi.org/10.3390/antiox10010085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827235/
https://www.ncbi.nlm.nih.gov/pubmed/33435216
http://dx.doi.org/10.3390/antiox10010085

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